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Studies on Tumors of the Thyroid

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Trial Phase

Enrollment Quota
Trial Size
Specialty: Endocrinology,Internal Medicine,Oncology
Subspecialty: Endocrine Oncology,Thyroid/Parathyroid,Endocrinology,Hematology/Oncology,Endocrine Oncology
Sponsor: National Institutes of Health Clinical Center (CC)
Study Start Date: May 1977
Estimated Completion Date: Not specified


No interventions cited

Inclusion criteria

  • Adults and children with known or suspected thyroid neoplasm will be considered for participation. Enrollment will be capped accordingly:
  • Patients with thyroid nodules requiring evaluation and possible biopsy (no more than 30 per year)
  • Patients with recent diagnosis of thyroid cancer requiring consultation and counseling about therapeutic options (no more than 10 per year)
  • Patients with established thyroid cancer requiring specialized studies such as (131)I dosimetry (no more than 5 per year)
  • Enrollment of high risk, non-iodine avid, inoperable thyroid cancer only for purposes of screening for eligibility for other specific thyroid cancer protocols

Exclusion criteria

  • Serious underlying medical conditions that restrict diagnostic testing or therapy such as renal failure, congestive cardiac failure or active coexisting non-thyroid carcinoma
  • Patients unable or unwilling to give informed consent

Study Locations And Contact Information

  • National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda Maryland
    Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL) 800-411-1222


Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer. The main purpose of this study is to further understand the methods for the diagnosis and treatment of thyroid nodules and thyroid cancer. Many of the test performed are in the context of standard medical care that is offered to all patients with thyroid nodules or thyroid cancer. Other tests are performed for research purposes. In addition, blood and tissue samples will be taken for research and genetic studies.

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