IN BREAST CANCER, AND MELANOMA
OBTAINING SENTINEL NODE HAS BECOME A PREOCUPATION
UNLESS WE REALLY NEED TO (SUCH AS CHECKING FOR MORE ABNORMAL GENE) can we just check VGEF D.
(rattling the cage at CRBCM)
can't make up this stuff:
"
Tumor metastasis to lymph nodes:
Lymph node metastasis is very often associated with several types of
human malignancies. Cancer cells’ journey to lymph node takes place
largely through lymphatic tunnel located in and around of primary tumor.
VEGF-D’s interactions with VEGFR-3 predominantly expressed in lymphatic
vessels plays a key role in restructuring lymphatic channel and, hence,
able to alter its functions related to fluid and cell transport along
the conduits. VEGF-D has been established to be over-expressed in both
tumor tissues and patients’ serum samples in several types of human
cancer. In addition, VEGF-D expression has been implicated with
increased incidence of regional lymph node metastasis. In experimental
mice study, genetically modified tumor cell that was forced to produce
VEGF-D protein have been established to boost up regional lymph nodes
metastases.[2]" wikipedia
and instead of the c-FOS, dose the FIGF,
INSTED OF .....DON'T LET ME STARTED NOW, GO WITH WHAT YOU KNOW!
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