Saturday, November 15, 2014

Amplification of NCK-2 gene is/could be a strong Bio-marker of cancer recurrence

One thing for sure the return of cancer is physiologically one of an extraordinary undertaking in cancer biology.  Indeed as cell reconstitute, reoganization has to occur at several cancer cell levels including the Cytoskeleton.   One of the little known gene that comes into play is the NCK2 gene, a ligand protein /gene that direct to exacerbation of Actin polymerization and " The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization" wikipedia.    We suggest, It is strong signal that the cancer is back!

BE CAREFUL NOW THIS IS DEFINITELY NOT THE NEK-2 GENE, AN ALL OTHER  GENE INVOLVED RATHER WITH THE AURORA!

LET US FOLLOW IT IN OUR CANCER PATIENT PARTICULARLY THOSE ON TAXOTERE!
MAY BE ADD HEF-1, LIMS1 FOR THE FUN OF IT!
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