Coalition for the Reversal of Breast Cancer Mortality in African American Women

A blog about research, awareness, prevention, treatment and survivorship of Breast Cancer and all cancers, including targeted scientific research and a grassroots approach to increase screening for cancer, especially in the low income and under-insured population of El Paso, Texas, with a view to expand this new health care model to many other 'minority' populations across the United States and beyond

Tuesday, December 31, 2013

THE CYTOKINE QUAGMIRE!

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Times and times again we land in this soft land of unknown, with the future of our patient potentially irreversibly compromised, despite a g...

Oncologist of today must be "MR Clean"

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The Beauty of target therapy is that you know exactly, at least you feel like you know, what you have done, and could possibly predict the r...

AN EXCITING HIDDEN PEARL in triple negative breast cancers.

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Hidden beneath the mantle of "triple negative breast cancer", one wonder if there is still to be discovered a sensitivity to Estro...
Monday, December 30, 2013

Tankyrase, an important target in triple negative breast cancer!

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If the concept is right and with the advent of the importance of vesicular formation and displacement of cellular protein as a major distur...
Sunday, December 29, 2013

FARNESYLATION, FRIEND OR FOE

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The ascent of KRAS as a therapeutic biomarker in Metastatic Colon cancer has increased the interest in Farnesylation as cellular process bec...
Saturday, December 28, 2013

Dupplicity of MITF( microphthalmia-associated transcription factor)

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One of the gene that tells us that we are still at the dawn of big genetic discoveries is MITF. The NCBI tells us "This gene encodes a...
Friday, December 27, 2013

Current treatment of Gastric cancer (New patient at GECC)

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Local disease Surgery cure rates in node negative diseases 75 to 20% for stage III (node positive)  5 year survival  20-25%  (the reverse...
Thursday, December 26, 2013

Biomarkers' controversy in Medicine

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As we see our volume of patients expand by overtaking other Doctor's business, there is this growing notion that we will be alright if ...
Wednesday, December 25, 2013

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This year the American Society for Hematology (ASH) took place in New Orleans and no one participant has left without hearing about CARs C...

FOR THOSE OF US WHO FOLLOW CPRIT LIFE CLOSELY

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GO TO THE ARTICLE BY JAMES DREW TO BE FULLY INFORMED (DALLAS NEWS) Ex-official indicted over $11 million Texas cancer-fund grant  BY JAME...

ACTIVITY AT CRBCM 2013

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MERRY CHRISTMAS TO ALL This was the first year of CRBCM AND WE REGISTERED OVER 33,000 REVIEWS OF OUR BLOG WHICH NEEDED TO BE CREATED TO F...
Tuesday, December 24, 2013

FOR THE CURE, PROMOTE APOPTOSIS!

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For cancer cell killing, no one can do it best but the cell itself through it's programmed death process we come to know as Apoptosis.  ...

IN BRAIN CANCER, THE INTRICACY OF THE RAC AND RICS GENES, THEIR DANCE WITH THE TIAM1

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There is no underdog gene or gene not fully recognized for its power than RAC-1. yet it is a pivotal gene.  RAC-1 belongs to the Rho family ...

WHAT VITAMIN D GOT TO DO WITH c-MYC ANYWAY?

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Yes it is true that there is a potential link between Calcitriol (the active form of Vitamin D) and  the master genetic amplifier c-MYC, a b...
Sunday, December 22, 2013

PONATINIB, A COMEBACK KID!

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GOOD THERAPIES ARE DIFFICULT TO DIE A DRUG JUST RECENTLY STOPPED BY THE FDA, IS RETURNING TO THE MARKET FOR SPECIFIC INDICATIONS WITH A WO...
Saturday, December 21, 2013

Description of Spindel Cell Sarcoma and why inflammation and injuries can lead to spread of malignant cells

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Spindle cell sarcoma From Wikipedia, the free encyclopedia Jump to: navigation , search Spindle cell sarcoma is a ...
Friday, December 20, 2013

Determined to lead to the recognition of the CRBCM! Promoting standard Care!

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Thursday, December 19, 2013

We are not the only ones looking into Sirtuins and how to reduce cellular stress response in the Brain:

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Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes ...

Too little, too late!

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In a living cell, things are constantly happening, nothing is still,  molecules are constantly cross talking so to believe that lipid depos...

GENE WORK INVOLVING Breast CANCER SURVIVORS

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With significant progress being achieved in cancer therapy, we are finding ourself living with our sisters and few brothers who had gone thr...

TRYING OUR BEST TO TALK TO THESE GENES IN BREAST CANCERS: MED1,6 and 12

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With the clinical finding that Bicalutamide, a non steroidal anti-androgen, has a role in some of the luminal forms of Breast cancers, genes...
Wednesday, December 18, 2013

Proof that target therapy has come in to change things in cancers!

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1.Combining Ibrutinib with R-CHOP is not only feasible but yield 100% response in Diffuse Large cell Lymphoma. For decades, CHOP had remai...
Tuesday, December 17, 2013

Dr. Kankonde MD the new physician and custodian for Dr. Lundy's patients in El Paso Texas

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The CRBCM, expanding its foot print in El Paso.  We are in the right fight because our cause is just!

Collaboration at the CRBCM, good progress in our lung cancer research! We thank MDHonors, UTEP, LCBRN/Univ. of Virginia tissue Bank!

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12/16/2013 "Hi Peggy, Attached is your invoice for the 45 RNA samples and 50 serum samples that you recently requested from the LC...
Monday, December 16, 2013

PIM1, a powerful target in Cytokine dependent diseases

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No gene is deep in the bowel of the cellular Beast having such powerful interactions that leads to cytokine production as this one.  Its rel...

The secret of triple negative breast cancer

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Common sense tells us that events happening in your women when they acquire childbearing age contribute significantly to the happening of tr...
Saturday, December 14, 2013

IN THE "EL PASO TIMES"

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There is an announcement for the last 2 Sundays, reporting the Retirement of DR RAY LUNDY, a Dr who has been a pillar in this community. D...
Friday, December 13, 2013

CRITICAL POTENTIAL NOTIONS IN UNDERSTANDING TRIPLE NEGATIVE BREAST CANCERS

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It all makes sense that Hypoxia induced by respiratory failure in a predominantly obese population will contribute to generation of Reactive...

An interesting Observation

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  Contact QIAGEN OUR SOURCE FOR QUESTIONS!  A study on a  BRAF(V600E) melanoma cell line treated with RAF, MEK, ERK or combined RAF-MEK in...

GENES IN MELANOMA

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ERCC6 DDB2 POLH RAD2 p16/CDKN2A, p14ARF CDK4 MCIR NRAS BRAF KIT MITF PTEN GNAQ GNA11 XPA BRCA miRNA 1.does amplification o...
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Peggy Kankonde
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