Monday, February 17, 2014

What can we quickly improve through Gene interference! Questions?

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*Do various viruses who require intracellular multiplication also require use of EIF4G? *Can blocking Cap dependent transcription through ...

Whims of hope are driving the fight for the cure!

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We know we will never win all human competitions which are marred with intrigues, but because our cause is just, because the cause is what...

The CRBCM, man enough to show-up!

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his is a confirmation e-mail for the following: Grant-maker: National Cancer Institute - NExT Program Program: NExT Partnership with NCI ...
Saturday, February 15, 2014

New Consults!

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Today 3 new consults at CRBCM referred by UMC network!, 1.Pancreatic 2.Renal cell cancer 3.Hepatoma opening a panoply of genetic abnorma...

The Internist's Tumor

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No tumor remains of interest as Renal cell cancer, and the interest keeps swelling not only with the incidence of the disease, but with vari...
Friday, February 14, 2014

Testing the general population for cancer risk!

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It is now set! Our research in cancer predisposition in the general population is shaping up, the consent has been drawn, where to keep the...

NOTES TO EXPAND ON!

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Resveratrol, in aging and cardio-protection controversy! Enzastaurin; inhibitor of Protein Kinase C Beta Panobinostat ABT-199---BCL-2 INH...
Wednesday, February 12, 2014

Meeting at UTEP with DR Zhang and DR CHOI

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2/11/14 Monthly meeting to mark completion of the first phase of the lung cancer project.  This is preliminary completion of gene detection...
Tuesday, February 11, 2014

is c-fos over expression protective for Colon, Gastric and Bladder cancer? question of the day!

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Is c-fos expansion or overexpression protective for Colon, gastric, bladder cancer (we are open to an opposite result)  THIS IS INVESTIGATIO...

more genetic based questions (?future role of Ibrutinib-the wonder drug?)

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*Role of Caveolins in stroke and MI. Does this scaffold matter in these disease?   *what links Psoriasis, breast cancer, androgen, c-MYC, a...
Monday, February 10, 2014

A little story into genetic investigation leads me to CPRIT and Alfred Gilman.

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2 days ago a man I am following  for basic medical problem and follow-up, called my clinic. One of his daughter who is obese and diabetic w...
Sunday, February 9, 2014

more questions

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Tankyrases are definitely the next gene to inhibit is NME1 the determinant of whether or not a tumor is metastatic, what about NM23-1,2 is...

Genetic work cogitations

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*Should we forget DNA effect, and plunge on epigenic dysruption of etoposide and slowing of processes at the Mitochondria as mechanisms of a...
Saturday, February 8, 2014

CRBCM is now affiliated with Vista College of El Paso

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The CRBCM/Greater East Cancer Center is now affiliated with El Paso Vista College to provide administrative and clinical ground for trainin...
Friday, February 7, 2014

What is cancer cure anyway.

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It is easy to globally point out cure for cancer patients, if the patient is staying alive after a clear diagnosis of a cancer that is remot...

Keeping the role of MITF, RUNX3 and SIX3 in perspective (keeping notes)

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something is definitely cooking here,  just need to put my finger in it!                                                 DAPK            ...
Thursday, February 6, 2014

The value of Water! (scientific speculations)

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Every time it comes to mind that we need to explore further the quantity of 2-3 things in our body to prevent stroke and Myocardial infarcti...

Activity at CRBCM: Preliminary results seem to concur!

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Already the first phase of results from the study funded partially by the CRBCM and MDHonors are completed.  This is a study on lung cancer ...
Tuesday, February 4, 2014

TRPM7 (and PLBC)

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It is potentially a dangerous gene when mutated (TRPM) Its autophosphorylation capacity makes it a potential DRIVER gene... And it is an I...
Monday, February 3, 2014

Meaning of cancer recurrence

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1-Meaning of recurrence 2-disease only slowed down 3-new development of new bypass pathway 4-additional escape mechanism or pathway 5-re...
Sunday, February 2, 2014

Then it goes on to destroy the quote: another political game by excluding us! can't make up this stuff !

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just a reminder and CRBCM agrees with the following quote: "The best discoveries in science aren’t predictable,” says HHMI President...

NEVER LEAVE YOUR MIND AT PEACE WHEN IT COMES TO GENES (PROGNOSIS OF SENESCENCE)

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It is by now quite clear that Senescence is clearly linked to the health of your eyes (given the frequency of cataract in elderly) and intri...

ACTIVITIES AT CRBCM AS OF FEBRUARY 2014!

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It is critical to our readers to know that CRBCM is still alive, maturing and quickly expanding its reach... It is mind "troubling...
Friday, January 31, 2014

Many Invitations, so little time!

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 SENT TO CRBCM =================================================================== Good morning, The Office of Continuing Medical Ed...
Thursday, January 30, 2014

In Lymphoproliferative disorder, particular of dangerous genes

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1*Highly conserved Molecule:  This means the molecule has stood the test of time and has been used under that form for years, and may have b...

New Challenges to the human cell

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In a world where new stimulants and new conditions are created, the human cell, deep in our systems, is confronted and forced to adapt and c...
Wednesday, January 29, 2014

Diet is important in cancer control:(case in point, Breast cancers!)

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I knew this from the Bottom of my heart but pinning the genetic reason was here before me and I just did not see it.  Supply of sugar will ...
Tuesday, January 28, 2014

Questions for researchers! Melanoma as an example !

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When a cancer continues to rise -it means it is more environmental? -It means its central mechanism continue to escape us -It means the i...
Sunday, January 26, 2014

Puzzling c-KIT

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C-kit presence has been used in the definition of GIST and its presence has been used for the sensitivity to TKI (Gleevec).  But this is pro...

In Melanoma, Tribulations of the MITF gene!

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The gene is a "wild" gene and can auto-regulate, 2 charateristics that make MITF a dangerous gene!   Moreover, it is implicated in...