Sunday, March 30, 2014

LOOKING DEEPER INTO THIS

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IS IT THE CYTOKINES AGAIN? how to detect vascular health? objective 130/80 biomarkers for detecting risk of stroke, A-fib, ESRD,periphera...

Cytokine Bank!

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Nothing will produce such a bounce in medicine there no parallel in progress in medicine but constitution of a cytokine bank will have the...
Thursday, March 27, 2014

ZERO-ING ON MEMBRANE PHENOMENA

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*Metastatic processes are facilitated with depression of E-Cadherin but are PKP2 also depressed or overexpressed does the processes of met...
Wednesday, March 26, 2014

looking into new targets

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Casolaro et al " Recently Polo-Like Kinase 1 (PLK1) has emerged as a new candidate drug target in AML." but evidence is imposin...
Sunday, March 23, 2014

from those who know the regulators of major pathways!

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"Nde1, Lis1, and Brap regulates the dynamic MAPK signaling threshold in a spatially dependent fashion. Brap, a mitogen-activated protei...

Careful what you read

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In cancer reading, one should be careful because so much remains unknown most of the time, the reader is exposed to the writer interpretati...

looking into cancer resistance and the autoimmune syndromes

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-Does chronic exposure to autoimmune diseases or antigen stimulate a new set of genes -does these gene include genes from cellular growth ...
Saturday, March 22, 2014

Another Local hospital will accept our patients

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It was long awaited another Large local hospital will start accepting greater east cancer center patients Del Sol Medical Center , has a...
Thursday, March 20, 2014

Evidences increase that FOXO3 (HYPOTHESIS)

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FOXO3 is the reason why inflammatory processes and other causes (such hyperhomocysteinemia) DO NOT INDUCE CELLULAR PROLIFERATION.   DURING...

how to stay young

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first you have to know all your genes and every time you want to ingest something, know the genes in what you eat and think that you are ab...

Instead of exercising, why not decrease the DAF 2 gene? (suggestions from the literature

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"Decreased DAF-2 signaling also causes an increase in life-span." kimura et  al! or is it the Insulin line "Reduced signali...
Wednesday, March 19, 2014

questions of the day in stroke or myocardial events

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What weakens the blood vessel for stroke to occur is it an acute process is it a long standing transformation due to or inducing cytokine ...
Tuesday, March 18, 2014

And Researchers have done the work

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And as we have suggested, down the belly of the beast, the dance was uncovered...and for triple negative breast cancer, we now know that the...
Monday, March 17, 2014

An interesting Target: The Cullins

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" the F-box protein p45(SKP2) is required for S phase and forms stable complexes with p19(SKP1) and cyclin A-cyclin-dependent kinase (...
Saturday, March 15, 2014

Activity at CRBCM

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As we plan another Visit to the Indianapolis Area this week-end the CRBCM has rapidly grown to meet an accelerating demand of immediate pati...
Tuesday, March 11, 2014

Questions in Pancreatitis

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1.Complications from pancreatitis results when a Cytokine storm complicate the clinical tableau, which Cytokine? can we stop the buckling ...
Monday, March 10, 2014

CRBCM keeping alive is a battle in a cut throat world!

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This email is to inform you that your Attestation for the Medicare Electronic Health Record (EHR) Incentive Program is 'Accepted'. ...
Sunday, March 9, 2014

speculations in lung cancers

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1.TTF-1 and CK 7 held as biomarkers of lung origin, how does MUC 7 compare? 2.how does T790M confer resistance to EGFR positive lung cancer...
Saturday, March 8, 2014

Progress in leukemias with the CAR-T Cell

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Genetically engineered autologous T cell fight blood cell cancers seem to attract attention of researcher lately. these cell work with CD19 ...
Friday, March 7, 2014

Authors working quickly on the TRB3, a center gene for rapid understanding!

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Homocystein can block cell proliferation by upregulating p27 which reportedly increases phosphorylation of AKT.Phosphorylation of the AKT al...
Thursday, March 6, 2014

Still at work, the CRBCM...

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It is conceptually correct that main events such as Heart attack or strokes be preceded  by an outburst or an overall increase of either an...

Questions in limited Area of knowledge, focus on Vitamin D

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1.Does intake of high dose Vitamin D decrease sensitivity to Androgen Meaning Could it help in Prostate cancer Prevention 2.could dimeriza...
Wednesday, March 5, 2014

Activities at CRBCM

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1.We have been busy, extremely so.... new patients in the work 1. Patient with Polycystic Kidney, Hypertension, we need his genes to see w...
Friday, February 28, 2014

In our lung study! fascinating MDM-2 Mutation? (AT UTEP WITH DRS ZHANG AND CHOI)

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The MDM2 amplification/Mutation was the highest finding and remain persistently present through the various stages of lung cancers making it...

Work still to be done in survivors

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One of the aspect of cancer treatment that remains to be clearly categorized in most cancers including our focus:Breast cancers, is how to b...
Wednesday, February 26, 2014

AND IT KEEPS HAPPENING FOR THE" WONDER" DRUG

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FROM MEDSCAPE: "The FDA has given accelerated approval to ibrutinib (Imbruvica) for treating CLL in patients who have undergone at l...

CAN YOU PLEASE GET ME TO MELBOURNE, SCIENCE WILL ACTUALLY OCCUR THERE!

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"The 2014 meeting of the International Cytokine and Interferon Society is to be held in Melbourne, Australia, during October 26-29, a...

INSTEAD OF TORTURING PATIENT WITH NODE DISSECTION, HOW ABOUT SIMPLY TESTING FOR VGEF-D

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IN BREAST CANCER, AND MELANOMA OBTAINING SENTINEL NODE HAS BECOME A PREOCUPATION UNLESS WE REALLY NEED TO (SUCH AS CHECKING FOR MORE ABNOR...

CSK random phosphorylation/related clinical questions

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FYN LCK LYN YES-1 HCK Src FRG BLK FRK 1.ATRA combined to Geevec as a way to break gleevec resistance? 2.disease with PDGF with S...

vain attempt but we keep dancing!

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Dear Peggy; You have been successfully registered for the following training event. ------------------------------ Title: SBA Lending F...