Wednesday, April 30, 2014

Natural laws at play in CLL-Theory

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In all the pathology, there is no disease that makes so much sense than Chronic Lymphocytic Leukemia disease I will beg to venture.  Our und...
Tuesday, April 29, 2014

Some genes of interest

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1.MTNR1B : A MELATONIN GENE " insulin levels also exhibit a nocturnal drop, which has previously been suggested to be controlled, at ...
Monday, April 28, 2014

Prevention and monitoring following cellular zones

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As predominant abnormalities of genes are more described as they are specific to each cancer, most likely location of genes in the cell coul...
Sunday, April 27, 2014

OUR OLD EXPERIENCE HELPS ! LAS VEGAS ROCKS!

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Yes as a drug gains more indications, the past experience makes it easier for Oncologist practitioner to re-use drugs they have been used to...

LAS VEGAS WILL STAY ON OUR MINDS FOR A WHILE, RESPECT SILTUXIMAB FOR THIS!

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*How in the world can you succeed this!  But Siltuximab did, BE INDICATED IN A RARE FORM OF A RARE PRESENTATION OF A RARE DISEASE... EVEN W...
Saturday, April 26, 2014

LAS VEGAS conference III Mantle cell

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We first saw the Death of CHOP/R-CHOP in this disease Now we see the death of Modified HyperCVAD Today we see the rise of Ibrutinib-Rituxa...

The Hematologic malignancy review has been completed in Las Vegas II....CLL

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In CLL *?review role of Thyrosine Kinase in CLL *Prognosi factor remains the same (17p deletion, 11q dletion, ZAP70, etc.) *CLL remains ...

The Hematologic malignancy review has been completed in Las Vegas I....CML

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In CML  (Information to be rechecked in the literature) -Cytogenetic recovery becomes even more important as it guides 1. quality of respo...

Potential future collaboration lead at CRBCM!

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"T hanks Peggy for your quick response, As I mentioned to you last week, there was a potential collaboration with an oncologist i...
Friday, April 25, 2014

CRBCM, on the move again

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Flying today to LAS VEGAS for a major hematology conference for our reader this is the annual update in certain Hematologic conditions a r...
Thursday, April 24, 2014

A critical Function down the neoplastic transformation : NPM1

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As we test gene mutations with the UTEP team, one of the Mutation detected in the sera of lung cancer patients was Mutation or over expressi...
Wednesday, April 23, 2014

And progress continues on CRBCM Blog! More than 40,000 reviews....

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Coalition for the Reversal of Breast Cancer Mortality in African American Women   ·   Stats   ›   Overview May 2007 – April 2014 ...

More than 40.000 reviews in less than 2 years! The CRBCM!

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With over 40,000 reviews, the CRBCM is advancing slowly but deliberately our cause is just that is why we are still alive, will stay alive...

Ramucirumab, FDA approved in Metastatic GE Junction and gastric cancer, but is-it all?

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May be Ramucirumab will work At CRBCM we have a patient who has Angiosarcoma in the liver who had a rapid progression on Gem-Taxane (in fac...
Monday, April 21, 2014

The process of Neoplasia in lung cancer, potential for screening through blood!

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Lung cancer, one of the leading deadly cancers for which screening has not clearly be established, has been one of the target of many resear...
Friday, April 18, 2014

We had our last meeting with DR CHOI at UTEP!

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Yes yesterday was our last face to face meeting with DR Choi a brilliant scientist working at UTEP with DR Zhang. She is returning to China...
Thursday, April 17, 2014

Dangerous precedent about VIAGRA, its connection to Melanoma!

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The risk association of Melanoma with Viagra raises significant fear for those who have no genetic background because Melanoma is still one ...
Monday, April 14, 2014

Hyperlipidemia "under the microscope", REDUCING RISK OF CORONARY AND BLOOD VESSEL DISEASES

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-does Xanthelasma, Corneal arcus, provide clues in triglyceride deposition in the artery -does minimal pancreatitis and similar induced inf...

Genes to Eternal life

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According to the US Government on Aging (at least seems to suggest) to have eternal life you have to have or know some of the genes...
Sunday, April 13, 2014

related questions? Personal record mind you!

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*Can use of Atra/retinoic acid improves Nexavar? *could decreasing Zinc by a chelator increase or decrease Metastic progression in the live...

What I got from the literature, if you didn't get it, you did not get it!

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That Inflammatory forces will 1. Increase -Fibrinogen/Fibronectin -alpha-Antitrypsin -Serum Amyloid A -C-Reactive Protein -Complement...
Thursday, April 10, 2014

search for the "OBLONG" pill.

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"Oblong man" rather than "circle man" infers less obesity Obesity is a growing issue in the United States and many want...
Wednesday, April 9, 2014

Mechanism of targeting for therapy

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*Receptor Inhibitor *ATP competitor inhibitor *DNA repair *Amplification of certain gene or proteins (EMSY) *Hypermethylation of certain...
Tuesday, April 8, 2014

Be There! from PER

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Having trouble viewing this email? View on web         Joyce A. O’Shaughnessy, MD     Dear Colleague, I i...
Monday, April 7, 2014

role of TPI gene in cancers

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OROSZ et al: "One of these, triosephosphate isomerase (TPI) deficiency, is unique among the glycolytic enzyme defects since it is ass...
Sunday, April 6, 2014

Delayed Response to Ipilimumab

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This case of delayed Melanoma response to Ipilimumab is clearly puzzling and raises the question of the appropriateness of our measurement o...

few investigation questions in various diseases

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What testosterone gene has to do with Hairy cell leukemia What HLA has to do with Hairy cell leukemia (why the incidence in black is lower?...
Friday, April 4, 2014

ALL STROKE PATIENTS UNDERGO A CYTOKIN STORM AND SHOULD EXPECT PTSD!

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And once again we tremble to recognize that all stroke patients will suffer PTSD or post traumatic stress syndrome even though it is the bas...
Thursday, April 3, 2014

New areas of investigation in cancer research

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Can Cisplatin be used to stop recalcitrant Viral hepatitis load  ? or a combination of Cisplatin and Sunitinib or Imatinib what is the rel...
Wednesday, April 2, 2014

Questions in Diabetes

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Importance of measuring residual Insulin by weight, how that affect control of DM type2 how does the level insulin affect the need for Insu...