Thursday, May 29, 2014

don't finger CRBCM, we are trying!

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I was literally stopped to be questioned about statements on my blog! it is a blog the statements although based on facts are inted to sh...

progress at CRBCM!

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The CRBCM is continuing to advance... we are completing our mission in Louisville Kentucky, with expansion into Indiana, from Madison to Se...
Tuesday, May 27, 2014

what that's means in termes of gene abnormality for humira

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The drug increases chances of getting lymphoma viral infection (hepatitis) TB CNS complications allergies immune reactions worsening o...

The case of Urothelial Cancer

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Greater east cancer center was referred a case of a 42 year old man with history of previous admission for Peptic Ulcer disease who had repo...
Monday, May 26, 2014

Case in point : Urothelial Cancer with plasmacytoid histology

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>the tumor is bad news 1.It is Multicentric, Multifocal, and therefore metastatic at time of diagnosis 2.Its signet rings characteristi...
Sunday, May 18, 2014

Genes with dangerous behaviors

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1.Do remember that in the selection of genes to silence, find one that causes a Malformation  when mutated or deficient i.e the BRAF gene ...
Friday, May 16, 2014

have you heard from the state

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State Health Commissioner To Today at 12:39 PM Nationwide Increase in Measles Cases   According to the Cente...

basic research 2

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Secondary malignancy When a receptor is permanently blocked Or destroyed When a gene is over stimulated When bypass activation exist and...

still a question today 2 years into this?

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Basic research idea Pattern of transcription genes cancer cell Vs normal cell using microarray technology as a way to identify critical ...

questions in liver cirrhosis

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A 65 year old African American man came for consultation he is known to have  Hepatitis C since 1982 when he first  noted jaundice He met ...
Thursday, May 15, 2014

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*New study attracting CRBCM attention: Glembatumumab Vedotin in Metastatic Triple Negative Breast Cancer (but comparison with Xeloda raise...
Wednesday, May 14, 2014

CPRIT meeting again

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The Cancer Prevention and Research Institute of Texas  (CPRIT) oversight committee is meeting again  May 21 2014? Observers are asking.......

Mighty puzzling lung cancer!

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In the United states along, over 225,000 people will be diagnosed with lung cancers and 160,000 people diagnosed with this disease, will di...
Tuesday, May 13, 2014

CRBCM,international!

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A nice complex of our readers! And thank you!  on 5/13/14 Entry Pageviews Sweden 15 United States 12 Poland 5 ...

WHAT METASTASIS TEACHES US

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One can imagine what happens in the process of Metastasis as followed.   A cell with malignant transformation has acquired genetic structure...
Saturday, May 10, 2014

NOTES FROM SAN DIEGO -PANCREATIC CANCERS

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*NO NEWS IN PANCREATIC CANCERS It is increasingly evident that 4 options are offered in Pancreatic cancers 1-Folforinox, the best regimen...

Biomarkers in Lung Cancer

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For the first time, almost one year after the Harvard people talked about it, I hear in this setting talking about testing in lung cancer a...

Question of the day (GIST and GiST again!)

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Could Ibrutinib conquers resitance in GIST particularly those from NF1? remember this is just a Mast Cell disease evem though Cajal is favo...

Hello SAN Diego California, Update in Oncology!

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The CRBCM is here to get updated in Oncology for the year 2014 many new drugs, many changes have occurred and we will have a chance to ope...
Friday, May 9, 2014

Somebody just needed to tell me! GIST, not everything is in the BAG (or known!) if you get my drift...!

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THE CLINICAL CASE : ================== A 50 year old Hispanic woman with history of Neurofibromatosis came to me in March  2014, she had a...
Thursday, May 8, 2014

Critical genes under review

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*Membrane action *Early in the pathway  *ability to recruit the caspases *Through its action by GTF2i  (TFII) it activates c-Fos promote...
Tuesday, May 6, 2014

Vicious circle of life!

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An 89 year old man was brought to my clinic because he had painful feet, he had to be carried. Just 2 days ago he was well walking to a loc...
Monday, May 5, 2014

Lung Cancer detection Going back to Basic!

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Our study on lung cancer detection got boosted by UTEP individual efforts, indeed the availability of some Antibodies to certain genes allow...
Sunday, May 4, 2014

STILL TRYING TO FURTHER PROBE THE LUNG CANCER DATA AT CRBCM

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LETTER TO OUR INVESTIGATORS would you please send us the list of the names of the 10 antibodies that Dr. Choi has also measured in the lu...

How about "Embryonal" and "Blastic appearance" inside information

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*According to Perez Moreno et al....E2A works in the depression of E-cadherin a phenomena which intervene in the metastasis of cancer...is ...
Friday, May 2, 2014

notes

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IN ALL *Cells are devoided of granules *presence of CD19, CD22 *leukemia Cutis ---- some of the prognosis factors elevated LDH high w...
Thursday, May 1, 2014

Notes on Myeloma, lesson learned (II)

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*If del 17 present -give RVD (revlimid, velcade, Decadron) *After first transplant, your options are: 1.Tandem Therapy  Vs  Revlimid 2.Ma...
Wednesday, April 30, 2014

Natural laws at play in CLL-Theory

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In all the pathology, there is no disease that makes so much sense than Chronic Lymphocytic Leukemia disease I will beg to venture.  Our und...
Tuesday, April 29, 2014

Some genes of interest

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1.MTNR1B : A MELATONIN GENE " insulin levels also exhibit a nocturnal drop, which has previously been suggested to be controlled, at ...
Monday, April 28, 2014

Prevention and monitoring following cellular zones

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As predominant abnormalities of genes are more described as they are specific to each cancer, most likely location of genes in the cell coul...