Tuesday, March 29, 2016

Striking Facts

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*Mutation of BRAF has been seen in all cases of Hairy cell Leukemia Is that mean that Cladribine  and Pendostatin need to be used in BRAF p...
Friday, March 25, 2016

Today's GIST

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1. Standard treatment is Imatinib for 3 years for patient with high risk of recurrence those with Exon 11 in the KIT gene will respond the...

More and capable Telescopes

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when it comes to observing the Universe,  with our current means, comparison has been made that we can only look from our stand points.   B...
Thursday, March 24, 2016

Death Center

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*There is nothing without substance for smoke to exist there must be fire at origin and since death is a phenomena, a death center must ex...
Friday, March 18, 2016

Important Updates

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*90 % of lymphoplasmacytic lymphoma have L265P *Rituxan-EPOCH back into Burkitt lymphoma treatment *the infamous S1 better than Gemzar in ...
Wednesday, March 16, 2016

Lets back up a bit

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It is hard to imagine that as you are reading this, you are indeed traveling at 63,000 miles around the Sun but it is true.  We should be di...
Friday, March 11, 2016

Views on Colon Cancer Prevention

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The frequency of occurrence of Colorectal Cancers is attracting the attention of Researchers It seems though that the occurrence of Cancer ...
Wednesday, March 2, 2016

A second look

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Can we disrupt this through the UPF-1 " Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes ...
Tuesday, March 1, 2016

It just follows therefore

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It Just follow therefore that IDH-1 would be a Biomarker for use of Temodar and 5-AZAcitadine or Decitabine for Gliobastoma and may be add...
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Monday, February 29, 2016

In life, All go in pathways

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If you understands that life is hidden in pathways, you know half of the truth...and yes if you can touch A and B you may finally reach C an...
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Thursday, February 18, 2016

And it goes on

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With millions of suns in our Gallaxy (the Milky way )chances are there could be a earth like life comparable to ours.   But given the rando...
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It gets complicated

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from Myriad"Myriad’s newest companion diagnostic, myChoice TM HRD , is an algorithmic measurement of three biomarkers associated with...
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Monday, February 15, 2016

Life Mysteries

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Before you read this, take a moment to reflect about life as it is a mystery Mystery in its being, extent, dimensions and even purpose ...T...
Sunday, January 24, 2016

Perspective III

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Folks don't let it pass, right now today: "Mars, Venus,Mercury, Saturn, Jupiter" are in Alignment in over 10 years, a rare phe...
Saturday, January 23, 2016

perpective II

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Folks  I say these events "stretch my mind"  it really does.  In fact it gets you tired and at the long run can get you depressed....
Wednesday, January 20, 2016

Perspectives

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After a long pause due to disease-Prostate Cancer It is time to return to writing blogs or actually continuing the long reflexion on life w...
Thursday, March 26, 2015

Interlude

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We are back after Robotic surgery and 12 days of Intubation which has left us deconditioned Physical therapy is working with us now I c...
Friday, February 6, 2015

Articles review

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*Daratumumab added action to Revlimid and Decadron in Myeloma we are told! *New important pathway :  The PLK1 disturbing spindle cell assem...
Saturday, January 24, 2015

Cytokines and Vitamin D mysterious interaction...is there a value in Cancers of the elderly!

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"These sets of experiments establish clearly that combinations of recombinant cytokines and vitamins could induce substancial intramono...

Don't do it again in NSCL Cancers

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Clinically Negative phase III trials with Antiangiogenics (and their targets) in NSCL cancers: 1.Thalidomid  -----an Antiangiogenic drug ...
Wednesday, January 14, 2015

Castleman disease

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for Castleman disease Hepcidin, Arlet at al" The results of this unique case study (1) explain the mechanism of iron deficiency obser...
Saturday, January 3, 2015

about Vitamin D

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Dr David Samadi: "A University of Colorado Cancer Center study recently published in the journal Prostate presents new evidence that ...
Monday, December 29, 2014

Prospective study in cancer Neoplasia

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We are at the break of a large prospective study that will test our understanding of neoplastic transformation.  There are obvious facts tha...
Wednesday, December 24, 2014

JuntoBox Films

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JuntoBox Films
Tuesday, December 23, 2014

Options in Metastatic Her-2 positive Breast cancer

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1.Pertuzumab + Herceptin + Taxanes 2.Adotrastuzumab EMTANSINE  "a HER2 -targeted antibody-drug conjugate (ADC) which contains the hum...
Friday, December 19, 2014

New drugs on the market

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From Momenta: " Necuparanib (formerly M402)  is a novel, rationally designed, oncology drug candidate under investigation in metastat...
Wednesday, December 10, 2014

Cytokines after age of 45

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Now it is true that the Cytokines are able to induce cancers the question is is it through the FAK gene or the BCAR3,TENC1 or directly thr...
Tuesday, December 2, 2014

New targeting Chemotherapies

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Eribulin in Breast cancer Tipiracil in Colon cancer Ramucirumab and Paclitaxel (or FOLFOX) for Gastric cancer Panobinostat for Myeloma P...
Sunday, November 30, 2014

Recent Big news!

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*Recent trial suggested that Jakafi in combination with Xeloda may be useful in second line therapy against pancreatic cancer particularly t...
Tuesday, November 25, 2014

After the Cytokine period in a life cycle

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First we have a Conception, birth and growth lasting from birth to 10 to 15 years, this period is full of "growth" but seems domin...