ROLE OF SOX5, A DRIVER FORCE. FROM EPITHELIALIZATION TO METASTASIS

                                              TWIST1 ------!
                                                    !                !
                                                    !                !..................E-CADHERIN
                                                    !                !                                !
                                                 SOX5--------!                                !
                                                    !                        miR125B  - - - SNAIL-1------FGF
                                                    !                                                   !        !
                                                    !                                                   !        !
                                                    !                                              SIP-1  MMP
                                                    !
                                                    !
      _______________________!__________________________________
      !                     !               !                       !                !                   !
   COL2A        AGC-1       PPARs              AP-1        ATF1            C-jun