Showing posts with label greater east cancer center. Show all posts
Showing posts with label greater east cancer center. Show all posts

Sunday, November 3, 2013

4 Posters at 1st BIOMED Symposium, El Paso 10/26/2013

Dr.Zhang and Dr.Kankonde, Early Detection of Lung Cancer

 


 Dr. Kankonde, Immunotherapy in Ovarian Cancer




Dr.Kankonde, Decrease of TBI by early use of Butein, a Sirtuin Activator


Dr.Kankonde at 1st BIOMED Symposium El Paso, 10/26/2013


Dr.Zhang, UTEP, and Peggy Kankonde, Greater East Cancer Center


The true role of E-Cadherin Vs the ASSASSIN (destructors)

One of the main activities of cancer cells to complete their "criminal enterprise" is to escape proliferation control, and cancer cells have known this and have mastered the way to achieve this very efficiently through the Cadherins.  Though it is emphasized that the cancer cells reduce E-cadherin expression to free themselves from their neighbors by reducing Adhesion molecules, the truth is that there is a more ominous enterprise going on.  Degradation of E-cadherin through Ubiquitilation consumes or distracts E3 from its main job which is to remove some of the Inhibitors to CDK, LEAVING THE CELL WITH UNCHECKED CELL DIVISION.

Occupying the HAKAI  (ASSASSIN) would be helpful in achieving control of the process.

The E3 ubiquitin-protein ligase Hakai (HAKAI) also known as Casitas B-lineage lymphoma-transforming sequence-like protein 1 (CBLL1) is an enzyme that in humans is encoded by the CBLL1 gene.[1] This gene encodes an E3 ubiquitin ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation.

Monday, October 28, 2013

COLLABORATION AT CRBCM

A STRONG COLLABORATION BEING BUILT AT CRBCM
KEY MEETING THIS FRIDAY AT UTEP AND TEXAS TECH!

That is great!

I can reserve a small conference room (Bioscience Building Room 3.118) at UTEP. Would you like to give a brief presentation for your current project? If so, I can also prepare a laptop computer and projector.