OTHER TARGETS! WHAT IN HELL IS LEUKEMEIA INHIBITOR FACTOR?

THE LIST OF TARGET IS ENDLESS
EVERYWHERE IN THE CELL THERE IS MUCH TO FIND OUT
AND SCIENTISTS ARE SPEECHLESS
LETS DELVE ON THIS ONE
IN MATTER OF INTRODUCTION LET'S GO TO SHARKEY ET AL!

"Transcripts encoding the receptor for c-fms, the receptor for colony-stimulating factor-1 (CSF-1), and c-kit (the receptor for stem cell factor [SCF]) were expressed throughout preimplantation development. Other growth factor ligand and receptor transcripts were expressed in a stage-specific manner: these included receptors for interleukin (IL)-6 (IL-6R), leukemia inhibitory factor (LIFR), tumor necrosis factor alpha (TNF alpha) (TNFRp80 and TNFRp60), and gp130."

THIS STATEMENT UNVEIL gp130 AND ITS VARIOUS CO-FACTOR LOOMING IN THE DARK
DOING ITS THINGS, BUT IMPORTANT IN THE CYTOKINES LIBERATION AND ACTIVITY OF INTERLEUKINS. LEUKEMIA DRIVEN BY INTERLEUKIN-6 CAN BE MODULATED BY ACTING ON ITS RECEPTOR AND TARGETING TO  gp130 AND ITS SLEW OF CO-FACTORS!