HURTHLE CELLS:  Thyroid MALIGNANCY SHOULD BE A PART OF THE VON HIPPEL LINDAU SYNDROME.
It all makes basic sense.  There are significant disturbances in the Mitochondria of cells of patients with VHL syndrome.  These disturbances involve Mitochondrial DNA and Cytochrome Oxidase.  Multiplication of Mitochondria results, with the abnormal content giving the appearance of "Hurthle" cells!  This just hit me as I was looking into a new case of Hurthle cells, the patient had a History of VHL!

Curcio-Morelli et al. (Harvard institute) also described how VHL protein affects Thyroid hormone activation through de-Ubiquitination of regulating enzymes.