Wednesday, November 23, 2016

OPTIONS IN TRIPPLE NEGATIVE BREAST CANCER

1.CARBOPLATIN +  VELIPARIB

2.ABRAXANE    +   CARBOPLATIN

3.ADRIAMYCIN  +   CARBOPLATIN    +  TAXANE

WITH TAXANE WEEKLY X12
WHILE CARBOPLATIN IS GIVEN WEEKLY X 6

4LESSER ALTERNATIVE :   GEMZAR  (1000)+  ABRAXANE(125)


5.XELODA



OF NOTE: THE MORE THE NUMBER OF NODES INVOLVED, THE MORE THE BENEFIT OF ANTHRACYCLINS



FOR  METASTATIC DISEASE
1.ADD ENZALUTAMIDE  IN TRIPLE NEGATIVE WHICH HAS AN ADROGEN RECEPTOR POSITIVE, THERE WIL BE A 9 MONTHS BENEFIT

2.TARGETING GLYCOPROTEIN

3.PI3K
USE MTOR INHIBITOR
PACLITAXEL   +   AKT INHIBITOR

4.SNDX
ALEZOLIZUMAB  (1200 )+  ENTINOSTAT:   19%rr

ALEZOLIZUMAB  +  ABRAXANE

5.PARP INHIBITOR
OLEPARIB 400 MG PO BID
RUCAPARIB  600MG PO BID
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