NEW LIPOSOMAL VINCRISTINE WITH EFFICACY IN RELAPSE/REFRACTORY PHILADELPHIA POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA

AT 2.25 MG/m2 IV WEEKLY
COMPLETE REMISSION RATE 4.6%
WITH OF COURSE NEUROPATHY IN ALMOST 40% OF PATIENTS
BUT EFFECTIVE EVEN WITHOUT ASPARAGINASE
Liposomal encapsulation prolongs its presence in the blood and ability to penetrate the marrow, lymph nodes and spleen).
------------------------------------------------------------------
Jakafi, for your Myelofibrosis patient with positive JAK2V617F positive and negative patient
with a 35% reduction in splenomegaly at 24 weeks occurring in 41% of patients.
will check out the JAK signaling!