Showing posts with label extranodal infiltration. Show all posts
Showing posts with label extranodal infiltration. Show all posts

Friday, August 23, 2013

Questions in Hodgkin Disease

QUESTIONS IN HODGKIN DISEASE

1.WHY A BIMODAL INCIDENCE BY AGE ?
2.WHY HX OF MONONUCLEOSIS INCREASES 3X THE RISK OF HODGKIN DISEASE ?
3.THE INFECTIOUS PROCESS MUST LEAVE A DEFICIENCY FOR HODGKIN LYMPHOMA TO DEVELOP (HIV, EBV,  BONE MARROW TRANSPLANT) ?CD8, HLA DR (ACQUIRED IMMUNITY) ?
4.DOES EXTRANODAL INFILTRATION MEAN T-CELL INVOLVEMENT OR JUST FAILURE OF A BLOOD VESSEL ?
(to be continued)