They are numerous, most insidious and varied, yet impact the trends of our life in a deep, multiple ways. And we are just now trying to dig deeper in our understanding of these molecules. The Cytokines affect almost all aspects of our lives but unlike the hormones which induces changes at organs, tissues and system levels, they act at cellular level. Their functions are poorly defined because of this cellular level of action. But it is them that act on most receptors and ions channels to induce some the most vile and irreversible changes in cells, tissues and organs. And yet they remain unknown to the common living being!
A man asked, why we get fever during the course of an infection? I answered "your Cytokines"
Why I can't put up some weight when I have cancer or an autoimmune disease? once again the "cytokines"
Why people develop Post traumatic syndrome ? the Cytokines
why cancer cells get a growth advantage over local tissue in Metastatic cancers? if you guessed "Cytokines" you are right!
What do we give in adjuvant therapy after Melanoma resection? the Cytokine
What can cure Renal cell cancer? the CYTOKINES
What affects our Joints or induce Arthropathies when cholesterol is high (hyperlipidemia)? Cytokines for god sakes!
Why we get the features of getting old even in hiding? Cytokines....
and where in hell are your doctors not measuring these Cytokines....
The thing is that even we know they exist, nobody really knows to catch all of them, study them to their fullness...and use then to their potentials. And now that we are going molecular or I should say genetic with target therapy, we can probably make them synthetically...And I suspect their make up will be varied since they come from genes that are notoriously varied....
Cytokine banks are needed, and plasma centers collect them daily! put these facts together and make the math!
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