CANCER RESEARCH HYPOTHESES:

El Paso is proud to report that UTEP has a leading Research investigator,
Dr Robert A Kirken, PHD who gave an interesting talk about "New Concepts in Cell signaling and treatment Strategies", an excellent talk to say the least.

The CRBCM intends to approach him with many ideas that may lead to Cure.  I am sure he will tell us what makes sense and what is worth pursuing. These are some of the thoughts:

1.  We know that specialized cells such as Muscle cells become "silent" or "quiescent" when it comes to cell division. These cells lose their ability to multiply. Is cell division quiescence a potential cancer control mechanism?

2. The red blood cell during its maturation loses most of its nuclear material.  The residual cell or mature red cell continues its life delivering Oxygen with a half life of 28 days or so. Can we master the reason of persistence of life in a red cell as a target therapy objective as it comes to cancer control?

3.In some Hereditary Colon cancers, the mismatch repair in gene replication fails to trigger activation of P53.
One may ask if there is a coexisting abnormality of P53?
Is there a transcription factor inhibiting P53 Activation?

4.Pattern of transcription genes in basal cell type breast cancer Vs normal breast cancer.   (by micro-array or gene sequencing. Is there an opportunity for cancer therapeutics?

5. Alteration of pattern of receptor molecules on membranes of cancer cell.  Are some receptors specific to cancer cells?

and so on...

The list of opportunities for research appears endless,
We know cure is possible, let us go get it!  And CPRIT may help us!