BARRET ESOPHAGUS
*Characterized by a Metaplastic epithelium
*Risk factors include "GERD, white, Hispanic race,male sex, advancing age, smoking and obesity"
*Although low grade is still associated with cancer, preventive resection is indicated only in high grade dysplasia, the other needs to be observed!? go figure. Likely enough P53 Mutation presence will force the hand of the surgeon no matter the level of dysplasia!
* It is still unlear if medical management of GERD decreases occurrence of malignancy!? and 10-20% of symptomatic GERD have Barrett Esophagus (scoped population)
*One thing for sure HPV is more associated with the Squamous kind of Esophageal cancers!
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