NOTIONS ON CERVICAL CANCERS
Cervical cancers provide an opportunity for researchers to explore the pathophysiology of cellular interaction with a virus, and is a good example as to how a virus could lead to Cancer, and how, with a vaccine, one can eradicate or at least influence the prevalence of diseases including a specific cancer. World wide, 1 million people have cervical cancer and almost half that number will die of Cervical cancer. This point to an aggressive disease as compared to prostate cancer for example. The HPV related Cervical cancer is sexually transmitted, and in the United state up to 45% of women 25-29 year of age have tested positive in a particular study. There are over 100 types of HPV with the 16, 18 serotypes being the most cited as particularly prevalent. Their E6, E7 genes has been shown to incorporate themselves in Cervical cell genome. Other factors of causal nature include Smoking (which increases the risk of dysplastic changes at the Cervix), short interval between Coitarhe and Menarche, multiple sexual partners etc...Clearly use of condoms decreases exposure. Immunization is recommended for girls 9-26 years of age. Quadrivalent Vaccine has been advocated for boys to decrease frequency of Genital Warts and Anal cancers!
to be continued! NOW THE QUESTION IS SHOULD A BOOSTER SHOT BE ADVISED TO INCREASE COMPLIANCE?
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