Cancer prevention: A gobal failure of our current approach!

Our basic understanding of prevention is 2 fold or can be summarized in 2 main understanding scenarios
1: Stopping a continuous stimulation, or repression for that matter, of critical genes could prevent cancer:

- one suggests that the increasing rate of certain cancers can be justified by chronic stimulation of genes until an additional event happens to give an irreversible path to Neoplasia.  This understanding is prominent among Oncologists and the public for that matter, but our reaction is rather confused or ineffective.
The insufficiency of response is mainly justified by our limitation of understanding of what follows the the prolong exposure or stimulation, which form of gene (heterogeneic type) is more susceptible and therefore requires early preventive measure, what gene actually triggers the neoplastic amplification, how long an exposure is critical for any specific individual, what other concurrent failure needs to be there to induce or help the neoplastic transformation (ie. mutation of CYP gene)  and so on so forth...before these many questions, the human brain albeit scientific, has to stop.  And our stopping to computer these events has worked for cancers to keep killing.
IT IS TIME TO USE MORE COMPUTER POWERS TO PREDICT NEOPLASTIC DEVELOPMENT TO ACTUALLY INTERVENE BASED ON COMPUTER MODELS THAT WE NEED TO CREATE RAPIDOS TO STOP CANCER DEVELOPMENT.

Once and for all, we need to stop reading this:

The incidence of liver cancer is rising worldwide and in the U.S. mostly due to the concomitant rise in hepatitis C viral infection. Because liver cancer occurs in the background of cirrhosis, preservation of healthy liver tissue is critically important. Liver cancer arising from the hepatocytes ....(johns Hopkins)

THIS STATEMENT ACKNOWLEDGES THE FACT THAT WE KNOW THE CAUSE OF THE INCREASE INCIDENCE OF LIVER CANCER BUT THERE IS NOT MUCH WE CAN DO TODAY DESPITE OUR ADVANCES.  WE KNOW HEPATITIS C IS THE DRIVING FORCE BUT THERE LITTLE WE HAVE DONE SO FAR TO SQUARELY MEET THIS CHALLENGE.  VACCINE ARE ONE WAY...BUT FOR HEPATITIS C IT IS NOT AVAILABLE!

"
A hepatitis C vaccine, a vaccine capable of protecting against hepatitis C, is not available. Although vaccines exist for hepatitis A and hepatitis B, development of a hepatitis C vaccine has presented challenges.^[1] No vaccine is currently available, but several vaccines are currently under development.^[2]
One effort has involved use of the hepatitis B core antigen.^[3] In a 2006 study, 60 patients received four different doses of an experimental hepatitis C vaccine. All the patients produced antibodies that the researchers believe could protect them from the virus.^[4] Nevertheless, as of 2008 vaccines are still being tested.^[5][6] Some efforts have entered Phase I/II human clinical trials.^[7]
SynCon will test a new HCV vaccine in humans in 2013. SyCon's HCV vaccine can generate robust T-cell responses not only in the blood, but also in the liver—an organ known to suppress T-cell activity."WIKIPEDIA....


For cancer of the Gatro-esophageal (GE) junction, we read:
"The possible reasons of the rise (in the incidence of this cancer)  include the prevalence of obesity. elevated body mass index with increased incidence of GERD, and caloric consumption"  the author even suggests "Use of Aspirin and other non steroidal anti-inflammatory agents has been associated with lower risk of cancers of the GE junction and other gastrointestinal tumors"(Grothey)  YET THERE ARE NO NATIONAL COMPREHENSIVE PLAN TO USE THIS KNOWLEDGE.
REASON:  Insufficient knowledge about what else these medications can cause, from bleeding to predisposing to arrhythmia in some of us on various medications.  these fears block us from stopping these cancers.
IT IS TIME TO BRING IN THE POWER OF COMPUTER MODELS TO PLAN OUR APPROACHES!
(an exanple of gene suppression: CONTINUED SUPPRESSION OF PTEN! A PRECEDENT TO MANY DANGEROUS CANCERS! OR DECREASE OF E-CADHERIN...)

2. 2ND MAIN SCENARIO
IS USING FOOD SUPPLEMENT TO DAMPEN THESE STIMULATIONS OF GENE.
HERE THE ROLE ANTI-OXIDANTS IS CRITICAL.
WHAT I AM NOT SURE ABOUT IS WHETHER "FDA APPROVAL" STANDARD HAS HELPED OR DISCOURAGED PROGRESS IN THIS AREA...FURTHER PROOF OF CONCEPTS ARE NEEDED.  THE SUGGESTION THAT STATUS OF IRON, ZINC, MAGNESIUM AND OTHER MINERALS CAN MODIFY THE EFFECTS OF ANTI-OXIDANTS HAS BEEN INSUFFICIENTLY STUDIED.  SUSPICIONS ARE THAT WHAT IS GENERALLY GOOD AN INTERVENTION (TAKING VITAMINS, AND ANTI-OXIDANT FOOD STUFFS OR STAPLES, CAN BECOME DANGEROUS !  INDEED EVEN THE RATE OF CORRECTION OF IRON DEFICIENCY COULD BE DANGEROUS....DON'T GO TO FAST!)  ONLY WELL DESIGNED COMPUTER MODELS  CAN HELP US MANAGE ALL THESE PARAMETERS...AND WE ARE STILL NOWHERE NEAR THE GOAL!

WE NEED NEW BIOMARKERS FOR AUTOIMMUNE DISEASES...AGAIN COMPUTERS ARE NEEDED...WE CAN'T HANDLE THESE THINGS ON OUR OWN...THE EARLIER WE REALIZE THIS...THE BETTER!
CRBCM, WORKING ALWAYS!