Tuesday, February 25, 2014

And now it comes

In sarcoma particularly GIST
people seems to try Pazopanib added to Gleevec!
and Panobinostat seems the selected HDAC inhibitor of choice!
"
Panobinostat (LBH-589) is an experimental drug developed by Novartis for the treatment of various cancers. It is a hydroxamic acid[1] and acts as a non-selective histone deacetylase inhibitor (HDAC inhibitor)." wikipedia

In Gist, a sudden interest in the SRC gene!  more work for CRBCM, will look into this!
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