Wednesday, September 11, 2013

WHAT'S IN THE NEWS!

*reportedly dose dense Taxol carbo
with Taxol given weekly at 80mg/m2 day 1,8,15
and Carbo full dose AUC -6 given every 3 weeks
for 6 Cycles  showing better results in Ovarian cancer

benefit 10 months difference  Vs conventional chemoth. Q3weeks.
631 pts registered
stage II-IV

Dose dense in Ovarian Cancer!!!

*Once again no risk difference of treatment of breast cancer in pregnancy confirmed.

*Now old story
Metastatic Lung cancer
1st line if squamous---Gemzar cisplatin

1st line if non squamous -Premetrex-Cisplatin (AVASTIN)

BUT REMEMBER TARGET THERAPY SCREEN FOR EGFR, ROS,ALK 
ADD CETUXIMAB (TO VINORELBINE CISPLATIN PER FLEX)
CRIZOTINIB
NOW BEING CONDISERED LIGAND OF PDL-1.

*WHAT IS DOT1L  ?

*GANETESPIB, AN ANTI HEAT SHOCK PROTEIN INHIBITOR, THIS DRUG MUST BE MORE IMPORTANT IN LUNG CANCER PREVENTION!?

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