Critical genes under review

*Membrane action
*Early in the pathway
 *ability to recruit the caspases
*Through its action by GTF2i  (TFII)
it activates c-Fos promoter, this may play into response to therapy (Via TFII)
*SMARCB1, overall control of cellular growth (SWI/SNF)
*POLR2A
*XPB
*MED26
*TATAs
*CRK(L)

These are of interest at CRBCM