Saturday, May 10, 2014

Question of the day (GIST and GiST again!)

Could Ibrutinib conquers resitance in GIST particularly those from NF1?
remember this is just a Mast Cell disease evem though Cajal is favored?
Is GIST a basically RAS driven disease?
is the Anti-MEK  strong Alternatives to MTOR inhibitor in GIST?
Can Nexavar add to GIST treatment in NF1 diseases?
frankly based on my experience now NF1 presence is a clear clue to target treatment in GIST, the skin lesion tell the Oncologist I am here!  don't beat the bush!   But Gleevec and Sutent is not the real answers when NF1 is present!

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