Cancer cure is through death of cancer cell. To date, the main way of death for cancer cellis
through Caspase activation cascade. In most cells, we know the main
way the activation of Caspase occurs. That is Cytochrome C is naturally
anchored at the membrane inside the Mitochondria. The Anchor is in fact
a chemical bonding or attachment through electrons like molecules do
attach to each other. We believe there, Cytochrome C is attached to a
Cardiolipin which is part of lipid of the membrane. Just imagine
another molecule showing up with free electron, the free electron could
attract and pull the one involved in the attachment and break free the
Cytochrome C. Cytochrome C electron no longer attached comes out and
activate the Caspase (mostly Caspase 9 which eventually activates
members of its family) and there start the Caspase work to coagulate DNA
and genes start breaking leading to cancer cell death. One of molecule
that produces such disturbing free electrons, is Arsenic Trioxide.
This delivery of free electrons by arsenic trioxide is not limited to
the mitochondria. It occurs through the cytosol (liquid milieu of the
cell) disrupting many cellular pathways, delivering global intracellular
disruption. ( for those savvy people, do remember that the " breaking"
of the anchor could be induced from outside the Mitochondrial membrane
through the AKT or Bax effect--this is where Bcl-2 negative effect is
the strongest ) arsenic trioxide
This global
disruption has been established to treat Acute Promyelocytic Leukemia
(APL) (by the way, Chinese researchers lead the way on this one).
Frankly speaking, this "Global disruption"can be used in any cancer.
The problem is that it can occur in any cell, including our normal
cells. Giving caution to the amount you use because of a narrow safety
index.
Vitamin C and Microhydryn have also free
electron, that is why they can cool down free radicals and therefore are
called Anti-Oxydants . The free electrons of these compounds seem to
add to those of Arsenic Trioxide to Increase toxicity to the cancer
cell. It is worth mentioning that, at the DNA level, these free
electron break the strand, triggering our first law (activation of P53
and stoppage of cell cycle).
3 main problems
1. Good and bad pathways are stopped, mitigating the effects of global destruction.
2.
(non selectivity) Good and bad cells are killed. This effect is worse
in patients with poor reserve of free electron clearing molecules
(Gluthation based, Superoxide based and others). (CAUTION TO EVERYONE)
3. Arsenic is hard to get rid of, and chronic exposure signs will result.
But frankly speaking, you can use this to kill any Cancer. Research will continue at CRBCM no matter what!
Of Note: Use of this information outside of the topic discussed herein, is not endorsed by the CRBCM
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