NOMENCLATURE OF GENES INVOLVED IN THE 3RD LAW.

1.BIRC5  A CELL CYCLE GENE MAKING A PROTEIN REGULATOR OF CELL CYCLE AND APOPTOSIS MODULATION, SURVIVIN, IN BREAST CANCER IT IS A VALIDATED BAD PROGNOSIS INDICATOR.

2. BUB1
BUDDING UNINHIBITED BENZIMIDAZOLES 1
A SERINE THREONINE PROTEIN KINASE IMPORTANT A CHECK POINT.
LISTEN TO THIS, MUTATION OF BUB1 CAUSES ANEUPLOIDY, CHROMOSOME INSTABILITY AND PREMATURE SENESCENCE
DOES THIS SOUND LIKE A TARGET, I BET YOU!

3.  CCNB1
WIKEPEDIA SUGGESTS:
"
Cyclin B1 is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase of the cell cycle. The different transcripts result from the use of alternate transcription initiation sites.^[2]
Cyclin B1 contributes to the switch-like all or none behavior of the cell in deciding to commit to mitosis. Its activation is well regulated, and positive feedback loops ensure that once the cyclin B1-Cdk1 complex is activated it is not deactivated. Cyclin B1-Cdk1 is involved in the early events of mitosis such as chromosome condensation, nuclear envelope breakdown, and spindle pole assembly."

IF YOU DON'T SEE A TARGET HERE, CLOSE YOUR EYES!
CYCLIN B1 BEING AT THE "SWITCH" IS THE LATCH OF THE EXIT DOOR TOWARD CELL PROLIFERATION.  PRESENCE OF CYCLIN B1 COULD SIGNAL MALIGNANT PROLIFERATION.

4.CDC, CELL DIVISION CYCLE------MCM2  (TO BE CONTINUED)