*How in the world can you succeed this! But Siltuximab did, BE INDICATED IN A RARE FORM OF A RARE PRESENTATION OF A RARE DISEASE...
EVEN WIKIPEDIA DEFINE :
"Multicentric Castleman disease (MCD) involves growths at multiple sites.[8] About 50% is caused by KSHV, also called HHV-8, a gamma herpesvirus that is also the cause of Kaposi's sarcoma and primary effusion lymphoma,
while the remainder of MCD are of unknown cause. The form of MCD most
closely associated with KSHV is the plasmacytic form of Castleman
disease while another pathologic form, the hyaline-vascular form, is
generally negative for this virus."
BUT SILTUXIMAB IS:
"On April 23, 2014, Siltuximab was FDA approved under the brand name of Sylvant[11] for the treatment of patients with multicentric Castleman’s disease (MCD) who do not have human immunodeficiency virus (HIV) or human herpesvirus-8 (HHV-8).[12][13]"WIKIPIDEA
WATCH THE 2 AND GO FIGURE!
BUT LET'S GRANT IT, IT IS STILL AN ANTI-INTERLEUKIN- 6, A FACT TO BE KEPT IN MIND AS WE LOOK INTO TBI AND PTSD! CRBCM IS WORKING HARD!
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