AURORA KINASES,

A (like Australis)  is more important then B (like Borealis) because of  lack of therapeutic usefulness of the Borealis kind.

Mark my words, The Aurora Kinase inhibitors, by "disrupting centrosome function, spindle assembly, chromosome alignment" as reported by DR Roger Cohen, professor of Medicine at Perelman School of Medicine in a report by Devera Pine, are probably one of the most significant development target therapy.  These go to compromise of Mitotic division and growth inhibition.  These combine to Actin function (disruption of Microtubules) would trigger the second law of nature, triggering Cytochrome C realease and Caspases activation despite the presence of Bcl-2 presence.  And Alisertib could be the Agent to watch.  We believe a Taxane combination with Alisertib and an anti-kinesin will be a potentially  powerful combination to watch in Oncology!  These drugs certainly will make mitosis impossible and stop multiplying cancer cells in their tracks!   Neutropenia induced by the Aurora inhibitors is a concern in such a combination and growth factors will need to be used.  Cancer treatment is progressing by the day. The future is exciting and promising!