Sunday, January 6, 2013

ELF5 A NEW PROGNOSIS PREDICTOR OF BREAST CANCER THAT MAY BE SIGNIFICANT IN TRIPLE NEGATIVE BREAST CANCER.  ELF5 IS REPORTED TO BE THE PROTEIN STIMULATING MILK PRODUCTION. IN A BREAST CANCER CELL, IT FAILS TO DO ITS MILK PRODUCTION WORK BUT REPORTEDLY INDUCES GROWTH OF THE CELL PARTICULARLY IN HORMONE RECEPTOR NEGATIVE TUMORS.  POTENTIAL FOR TARGET THERAPY IS INFERRED.  

"CYP2D6 Has Impact on Effectiveness of Tamoxifen

Roxanne Nelson
Dec 31, 2012
Although previous studies have been somewhat inconsistent, a new study shows that breast cancer patients taking tamoxifen who have genetic alterations in CYP2D6 have a higher likelihood of both disease recurrence and death.
Approximately 5% to 7% of European and North American populations are considered to be poor metabolizers of tamoxifen, and there is a simple test that can identify these"
 FROM MEDSCAPE

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