* Esophageal cancers varies by types, and types are related to location
with the squamous cell cancer involving most of the upper 2 thirds of the Esophagus. It is this cancer that is linked to patients who are black, to Achalasia, caustic injury, Plummer -Vinson disease smoking and excessive alcohol consumption and to HPV. Adenocarcinoma are linked to GERD, Barrettt Esophagus, white race, smoking and obesity. It is also characteriZed by Metaplasia and Barett morphology
(to be continued)
Genes in esophageal cancers
Mutation of Rb1
and overexpression of Cyclin D1
MSR1, ASCC1, and CTHRC1
CDK4 and CDK6
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