New Medications in Refractory Myeloma

After failure of Revlimid, Velcade and Dexamethasone
particularly in Del 17 patient

4 options:
1. Elotuzumab + Revlimid + Dex
2. Elotuzumab + Velcade + Dex
3. Carfilzomib +Dex
4.Pomalidomid + Velcade + Dex

Newer options
- ARRY-520 +/- Low dose Revlimid +Dex
-DARATUMUMAB
-ANTI - CD 38 MONOCLONAL ANTIBODY.

NEW COMBINATION : REVLIMID+THALIDOMID +dex  IN BAD PROGNOSIS PATIENTS