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AZPG1
"Original Article
Oncogene 29, 5146-5158 (16 September 2010) | doi:10.1038/onc.2010.258
AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-β-mediated ERK signaling
Abstract
Epithelial-to-mesenchymal transdifferentiation (EMT) mediated by transforming growth factor-β (TGF-β) signaling leads to aggressive cancer progression. In this study, we identified zinc-α2-glycoprotein (AZGP1, ZAG) as a tumor suppressor in pancreatic ductal adenocarcinoma whose expression is lost due to histone deacetylation."It is associated with FAT/cahchexic losses in these patients
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TMPRSS2-ERG fusion
NKX3
c-MYC
PTEN
Favorable Gene hCAP-D3
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In Gastric Cancer
LOX
RASSF6
MR1
miRNA 107 (DICER1)
PDCD4
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In Colon Cancer
Annexin
S100A4
SERCA
GF15
BAX
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