THE QUESTION HAS BEEN RAISED: BIOTIN?

GIVEN THE IMPACT OF BIOTIN USE BY PATIENTS ON LEUCIN AND METHIONINE METABOLISMS, CAN BIOTIN USE COMPROMISE THE EFFECTIVENESS OF MTOR INHIBITORS? 
WE ARE GOING TO EXPLORE FURTHER THIS IMPORTANT QUESTION GIVEN THE GROWING IMPORTANCE OF MTOR INHIBITOR IN OUR ARMAMENTARIUM AGAINST CANCER AND THE WIDESPREAD USE OF BIOTIN IN OUR POPULATION!  (OR MULTIVITAMIN). WE ALSO KNOW THAT MOST OF US PRODUCE ENOUGH BIOTIN IN OUR COLON FOR DAILY NEED, BUT IS IT OF IMPORTANCE TO TRY TO SEE LEVELS OF BIOTIN IN PATIENTS WITH RESISTANT DISEASES?  IS DECREASING BIOTIN FROM THE BOWEL TO BE PURSUED IN PATIENTS ON MTOR INHIBITORS?  WILL SEARCH FURTHER THIS QUESTION!