WE ESCAPED SMARTLY IN THE MELI-MELO OF AGING JUST TO DIVERT OUR ATTENTION ON GENES INVOLVED IN ALZHEIMER. DON'T ASK ME WHY, BUT WE DID. WE CAME OUT MORE PUZZLED THEN ANYTHING ELSE!

MANY QUESTIONS THOUGH:

Many of the striking things and questions

1.Can calcium inhibitors slow down Alzheimer progression?
2. Is Namenda's role to slow down apoptosis in neurons by giving non specific stimulation to Glutamate receptors ?  Or this really by counterbalancing or increasing the effect of cholinesterase inhibitors? We know that when the disease is advanced and cell death has occurred, Namenda does not do much.
3. Can S100B be a more reliable way of monitoring Alzheimer's progression?
4. Does Alzheimer reflects a deficiency of Macrophage function and therefore Colony stimulating factors a way of treatment?
5. What is the effect of GM-CSF on NG2 glial cell and can this slow down Alzheimer?
6. What can slow down tau-protein phosphorylation, will ubiquitination work in detoxifying cells ?
7. What is the effect of disrupting the exosome, could this cause abnormal cell to be cleaned up earlier...? ....before plaque build up!
8. What is the real relation between Vit. D and DAG (diacyl glycerol), the phosphorylator, APOE and Presenilin?

Many question to struggle with...but the challenge is thrown at you, let's go to work!