*THE NURSE HEALTH STUDY WHICH FOLLOWED CLOSE TO 200,000 INDIVIDUALS REPORTED OR SUGGESTED ASPIRIN (325 MG ) REDUCED BY AT LEAST 23% THE RISK OF DEVELOPING COLORECTAL CANCER. AND THIS WAS IN ADDITION TO CARDIOVASCULAR PREVENTION BENEFITS. APPARENTLY, THE INHIBITION OF CYCLO-OXYGENASE (COX 1 AND 2 ) HAS AN IMPACT ON CELL DIVISION, APOPTOSIS AND ANGIOGENESIS!
*In Colorectal cancer
BRAF mutation is of poor prognosis (10 months Vs 34.7 months for wild type BRAF), tumor is diploid with Microsatellite instability! Give Vemurafenib!
*Intraperitoneal chemotherapy continues to show survival advantage in Ovarian cancers, despite the fact that the majority of Ovarian cancers with the relevant stage do not receive it!
No comments:
Post a Comment