Thursday, June 20, 2013

ASK YOURSELF, CAN YOU USE OF ANTI-TNF AND OR MACROLIDE IN COMBINATION OF ANTI-VIRAL ENOUGH TO CUT DOWN MORTALITY DURING A FLU EPIDEMIC?
AND WHILE YOU ARE ASKING YOURSELF THIS, I AM WRITING AN RFA FOR NCI.

The assumption here is that death from the flu is directly linked to TNF secretion and cyclins secretions under activation of the NF-kB, and these 2 drugs can tamper these 2 components/PATHWAYS.  check it out!

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ROLE OF BAFETINIB IN CMML AND MONOCYTIC LEUKEMIA
FOLLOWING THE LYN GENE DANCE!
SHOULD GLIMEPIRIDE BE CONTRE-INDICATED IN THESE DISEASES BECAUSE IT IS A LYN ACTIVATOR?
ACTIVATION OF LYN LEADS TO ACTIVATION OF INPP5D WHICH IS DEFINED AS FOLLOW: "Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[" AND THEREFORE A LEGITIMATE TARGET FOR THERAPY!

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