Sunday, June 9, 2013

REASON FOR OUR COALITION: THE BREAST CANCER PARADOX
RACIAL DISPARITIES IN INCIDENCE AND MORTALITY OF BREAST CANCER.
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Population based research have indeed  pointed out unique racial disparities into the prevalence and mortality of breast cancers in the United States. These disparities have been CONSISTENTLY occurring without being met effectively because of lack of political will by mostly white leaders, and a weak misrepresented minority populations (Hispanic and black population appear equally affected) which has not grasp the extent of this problem!  And the fact that it represents the LARGEST OPPORTUNITY  to curb mortality for this particular disease. (after Mammogram, hormone treatment, the BRCA discovery, are just some of the major interventions that curbed Mortality of Breast Cancer)

As stated above, these disparity have been consistently occurring years after years and grown into a sad phenomena well coined "The Breast Cancer Paradox".  People (researchers) have taken the time to coin it but relatively nothing is being done about it!  THE PARADOX IS FOUND IN THE FACT THAT THE INCIDENCE OF BREAST CANCER IN HISPANIC AND AFRICAN AMERICAN POPULATIONS IS LOW (YES LOW LOW LOW) AS IT COMPARES TO THE WHITE POPULATION.  BUT DID YOU KNOW THAT THE MORTALITY IN THE MINORITY POPULATION IS HIGHER (YES HIGH, HIGH, HIGH!).  BASICALLY MANY PEOPLE  (3000 (OUT OF 6000) AFRICAN AMERICAN WOMEN ALONE DIE A YEAR FROM BREAST CANCER FOR LACK OF INTERVENTION).

This fact has been described time and time again, it has been coined "Breast cancer Paradox", it has been looked at and ponder on, BUT NO EMERGENCY HAS BEEN DECLARED IN OUR TRILLION DOLLAR ECONOMY, NO PRIORITY HAS BEEN DECLARED, NO-ONE REALLY CARE ENOUGH TO RAISE THE ISSUE THE WAY IT SHOULD BE !

YET! The dichotomy has been observed years after years, and suscitated some comments some interest as a social curiosity can, or a scientific oberservation would.  But nothing comprehensive has been declared.  Our attempt to involve CPRIT has fallen in political quagmire and died with the CPRIT debacle.  The COALITION  will bring back the fore front!  It is a shame for this great nation to fail to recognize what is really happening with unchanged deaths in its minority population!

OF EVEN GREATER INTEREST IS THE OBSERVATION THAT:
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This Unique and deadly Breast cancer has unique charasteristics that strengthen the notion that it is genetic based.  Indeed the Breast cancers involving minorities, are mostly triple negative therefore cannot benefit meaningfully from 2 major therapeutic interventions:  Hormonal treatment and Herceptin and related drugs that seems the focus of our new drug developments.  Research seems to look the other way all together folks!  
Furthermore and to re-enforce the monolytic and genetic basis of the Breast cancer observed in blacks and Hispanics, up to 70% in some areas of these triple negative cases, have the unique Basal cell like morphology WELL DESCRIBED AGAIN. THE UNIQUENESS OF THIS PATHOLOGY SHOULD IN NORMAL CIRCUMSTANCES BEG AND CALL FOR IMMEDIATE INVESTIGATIONS WITH THE MEANS WE HAVE TODAY.   BUT SILENCE IS WHAT WE HAVE TODAY!

WE HAD HOPED THAT THE DISCOVERY OF THE HUMAN GENOME WILL BRING CLEAR ANSWERS.  BUT YES THEY DECODED THE GENOME OF THE TRIPLE NEGATIVE BREAST CANCER.  BUT ALL WE GOT IS THAT IT LOOKS LIKE OVARIAN CANCERS.  THAT IS DRUGS USED IN THAT DISEASE (TAXANE, PLATINUM) CAN BE USED IN THIS TRIPLE NEGATIVE BREAST CANCER, THIS WAS ALREADY IN PRACTICE, NO ADVANCEMENT THERE. SO WHERE DO WE GO FROM HERE. FOLKS ARE STILL DYING!

CRBCM HAS BEEN PUSHING FOR A COMPREHENSIVE - PRIORITY BASED PROGRAM BUT OUR EFFORTS ARE DYING IN DEATH EARS, NO POLITICIAN IS FULLY EMBRACING THE CAUSE!   CRBCM EARLY CONCERNS WERE SURVIVAL OF THE ORGANIZATION, NOW THAT GREATER EAST CANCER CENTER, THE PARENT ORGANIZATION, IS OF FIRM GROUNDS, AND WE ARE NOT GOING ANYWHERE, WE ARE LAUNCHING A SECOND WIND OF CONSCIENCE-RAISING-ACTIVITIES TO ADDRESS THIS DISPARITY IN CANCER RESEARCH.

CRBCM IS DEDICATED TO OPEN THE DOOR TO THIS EMERGENCY!  AND YOU CAN HELP!

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